WHAT'S NEW ABOUT PHYSIOLOGIC IMAGING?
One might retort that
functional imaging has been around for a considerable time with the
presence of gamma cameras in nuclear medicine, offering pulmonary
ventilation-perfusion scans; cardiac ultrasound, showing the motion of
the heart walls and valves; or standard biplane fluoroscopy revealing
joint kinematics or GI motility. So why the heightened attention to
physiologic imaging just now X-ray CT has evolved to where, with high
resolution CT we can begin to see structure, revealing regional lung
pathology at a resolution approaching the sub-millimeter level. Helical
CT provides the ability to scan a significant axial extent of the chest
or abdomen in single breath-holds. Magnetic Resonance Imaging has
reached imaging speeds whereby slice acquisition times are as little as
67msec. This, along with the electron beam x-ray CT's (EBCT) scan
aperture of 50 msec allows for the capture of the beating heart's motion,
the descent of the diaphragm, the passage of blood through tissues, and
the distribution of a breath tagged with radiodense gas. The effects that
air-water interfaces have on the MR signal are being used to estimate the
dimensions of pulmonary alveoli while to the eye there appears to be
little signal at all coming from the lung field in an MR image of the
thorax, and the use of hyperpolarized helium or xenon gas is allowing for
the imaging of lung structure via MR. Experimental MR and CT resolution
have been built which allow for resolution on the order of microns,
providing for the visualization of vessels at the very interface of
oxygen delivery to the tissues. Positron Emission Tomography (PET),
coupled with anatomic detail derived from x-ray CT and MRI, is yielding
images of the structure/functional relationships involved with perception
itself. The practice of radiology has always been highly dependent upon a
collaboration with physicists and electrical engineers. This team has
expanded to include the computer scientist, biomedical engineer, and
physiologist. While physiology departments around the country move
further away from what has become know as integrative physiology and more
towards basic investigations at the cellular and molecular level, the
frontier research in integrative physiology has moved into the clinical
departments of the School of Medicine, and into the School of Engineering
via the Department of Biomedical Engineering. Radiology faculty, as a
team of physicians and scientists, listening to and collaborating with
our colleagues throughout the schools of medicine and engineering hold
the key to the final pathway towards the understanding of ourselves as an
integrated living organism, and to use that understanding to dramatically
alter the practice of medicine.
What you will see on these pages are presentations of imaging and image
analysis aproaches which allow the physician and scientist to begin
quantitating and visualizing both structure and function. We provide
these presentations to stimulate discussion and to increase utilization
of such methodology. Additionally, we provide these presentations in
this format with the goal of making such advanced imaging technology
available to any site with the appropriate scanning facilities through
our teleradiology project.
3D Gallery: Here we provide a gallery of mpeg movies demonstrating volumetric
images of data obtained by various radiologic scanning methodologies.
Selected Papers: A collection of current proceedings
publications of DPI members.
PASS An online manual for
our Pulmonary Analysis Software Suite software package®. PASS is a comprehensive package
for the manipulation, display and analysis of multidimensional image data sets.
PASS is intended to assist doctors and researchers in the field of pulmonary research,
with lung segmentation, histogram analysis, hole measurement, and nodules and tissue
classification.
Current Projects:Find a description of our research projects.
Past Projects:
Here is a description of pass projects or software.
What's New! Find out the latest news and information
about DPI! Also find out about upcoming
conferences and submit your abstracts electronically.
Personnel All about the DPI
faculty, staff, students, and collaborators.
Contact Us Please email DPI
with questions and comments (good or bad).
Related Links Links to other University of Iowa sites,
Imaging sites, Physiology sites world wide and a reference site list.
TSIA:
Time Series Image Analysis program
performs perfusion and ventilation (blood-flow) analysis. Developed
within our lab.
Runs on Windows, Mac OSX, and Linux.
The concept of TSIA developed in early 1990s. Algorithm modules for
perfusion/ventilation parameter calculation are separated from GUI
and they are built as dynamic link library. Therefore any algorithm
dll can be switched depending on data set on runtime. This enables
algorithm developers can easily create their own algorithm for your
analysis.
The SPIE
Medical Imaging 2007 Meeting:
Feb. 17 - Feb. 22
at Town and Country Hotel, San Diego, California, USA
- Visualization and Image-Guided Procedures
- Physics of Medical Imaging
- Physiology, Function, and Structure from Medical Images
- Image Processing
- Ultrasonic Imaging and Signal Processing
- Computer-Aided Diagnosis
- Image Perception, Observer Performance, and Technology Assessment
- PACS and Imaging Informatics
American Thoracic Society Meeting:
May 16-21, 2008
Toronto, Canada.
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©1994-2007 Division of Physiologic Imaging, Dept. of Radiology,
Univ. of Iowa
Notice: Material on these pages is for non-commercial
use only and should not be re-distributed without written permission from the
Division of Physiologic Imaging, Department of Radiology, University of
Iowa.
On line since 10/17/94
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