Past Work

Application Specific Tutorials:

• Application Overviews
• Patient Scan Protocols
• Image Display and Analysis Methodologies
• Case Examples
• Bibliographic References with abstracts.

Courses

About VIDA^®:

CT Scan Image Storage and Analysis Center for the NETT

This is a contract to serve as the Image Analysis (and Archival) Center for the National Emphysema Treatment Trial. We will receive pre and post-surgery images over a three-year period from eighteen centers around the country for lung volume reduction. We will provide the image-based measures, which will be used in determining if CT provides outcomes predictors for surgical success. We will serve to provide the final imaging protocol for the study, image quality control, and we will maintain the integrity of the image database. This study hopes to enroll 2,500 patients. This will give us the opportunity to test some of our tissue characterization methodologies including basic histogram measures, as well as more advanced methods provided by our Adaptive Multiple Feature Method (AMFM). This is in collaboration with Johns Hopkins University.

Inflammatory Parenchymal Lung Disease Structure/Function

This project seeks to test the hypothesis that the earliest signs of inflammatory lung disease will be regional changes in microvascular mean transit time of blood flow. CT-based measures of both regional parenchymal anatomy and microvascular blood flow will be evaluated in normal and smoking subject populations. Both these populations will exhibit normal pulmonary functions. We will evaluate an animal model of emphysema from which we will be able to investigate sequencial relationships between blood flow alterations and parenchymal destruction caused by inhaled pancreatic elastase.

National Library of Medicine Teleradiology Project

The project's goal was to provide teleradiology between rural imaging centers with the University of Iowa. The rural sites would scan a patient and a team of physicians and technologists would analyze their image data and consult with the rural staff in real time.

Synergistic CT-Bronchoscopy for Lung Cancer Assessment

The project's goal is to help guide a bronchoscopist in biopsying enlarged lymph nodes in the lung with the use of the Virtual Navigator software developed at Penn State by Dr. Higgins' research group. The Virtual Navigator software uses a HRCT lung scan as input and provides many views of the lung field such as surface renderings, virtual bronchoscopy of the airways and 2D and 3D views of the CT scan. The Virtual Navigator's workstation interfaces to a standard videobronchoscopy equipment in the bronchoscopy lab. The bronchoscopist can then use the bronchscope and the tools of the Virtual Navigator to "navigate" to the lymph node and perform the biopsy. This is in collaboration with Pennsylvania State University.

CT Bronchoscopy Workstation for Lung Cancer Assessment

This project's goal is to devise an automated methods for CT-based procedure planning and image-guided bronchoscopy, thereby enabling more effective biopsy planning and subsequent bronchoscopic biopsy. The main idea is to development of the Virtual Navigator software/workstation into a more clinical friendly system by using the lessons learned from the previous phase I testing of the Virtual Navigator system. This project is in collaboration with Pennsylvania State University.

Last modified: Thu Nov. 16 16:29:21 CST 2000